Clive Landis, BSc, MSc, PhD

Role: Professor, Cardiovascular Research
Email: clive.landis@cavehill.uwi.edu

Dr Landis is Professor of Cardiovascular Research and the former Director of the George Alleyne Chronic Disease Research Centre, CaIHR. He leads the inflammation and wound healing programme in the CaIHR. He is presently seconded to the post of Deputy Principal, Cave Hill Campus. Professor Landis is the honorary Director of the Ministry of Health HIV laboratory, Barbados; past Chairman of the National HIV/AIDS Commission subcommittee on research, Barbados; Chairman of the Caribbean Cytometry & Analytical Society (CCAS); and past Associate Editor of the Journal of Clinical Cytometry; Chair, The UWI Regional Task Force on Zika (www.uwi.edu/zika).

Professor Landis received his PhD in Immunology in 1990 from Loyola University of Chicago, USA, where he also earned an MSc degree in Microbiology. He completed a postgraduate fellowship at Cancer Research UK before taking up a British Heart Foundation Lectureship in Cardiovascular Medicine in 1997at Hammersmith Hospital, Imperial College London, UK.

Professor Landis is a molecular and cell biology researcher. Using models of crystal arthropathies, cardiopulmonary bypass, atherosclerosis, and wound healing in diabetes, he has identified a key role for the ‘wound healing macrophage’, bearing CD163highHLA‐DRlowHO‐1high, in the resolution of inflammation. He is leading international efforts to redefine the systemic inflammatory response to heart surgery. Professor Landis also heads national and regional initiatives to expand laboratory capacity in the Caribbean.

Research interests

His research interests include inflammation, particularly the resolution of inflammation, in vascular diseases and recovery from surgery, and the expansion of HIV and molecular diagnostics in the Caribbean.

Selected publications

  • Landis, R.C., Carmichael-Simmons, K., Hambleton, I.R., Best, A. "HIV viral load trends in six Eastern Caribbean countries utilizing a regional laboratory referral service: Implications for treatment as prevention." PLoS One 10 (2015): e0125435
  • Landis, R.C., Brown, J.R., Fitzgerald, D., Likosky, D.S., Shore-Lesserson, L., Baker, R.A., Hammon, J.W. "Attenuating the Systemic Inflammatory Response to Adult Cardiopulmonary Bypass: A critical Review of the evidence Base" J Extra Corpor Technol 46 (2014), 197-211.
  • Landis, R.C., Branch-Beckles, S.L., Crichlow, S., Hambleton, I.R., Best, A. "Ten year trends in community viral load in Barbados: Implications for treatment as prevention." PLoS One 8 (2013), E58590
  • Landis, R.C., Arrowsmith, J.E., Baker, R.A., De Somer, F., Dobkowski, W.B., Ellis, J.E., Falter, F., Fisher, G., Hammon, J.H., Jonas, R.A., Kramer, R.S., Likosky, D.S., Milsom, F.P., Murkin, J.M., Poullis, M., Stump, D.A., Verrier, E.D., Walley, K., Westaby, S. "Consensus Statement: minimal criteria for reporting the systemic inflammatory response to cardiopulmonary bypass". Heart Surg. Forum 13 (2010), E116-123
  • Quimby, K.R., Greenidge, A.R., Harris, A., Landis, R.C. "Phenotypic commitment of monocytes towards a protective hemoglobin scavenging phenotype (CD14posCD163highHLA-DRlow) following cardiopulmonary bypass". Cytometry B Clin Cytom. 74B (2010), 357-360
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